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1.
Article in English | LILACS-Express | LILACS | ID: biblio-1385837

ABSTRACT

ABSTRACT: The objective of this study was to evaluate the relationship between oral health status and its impact on quality of life, and to suggest dental management strategies in patients undergoing antineoplastic therapy for onco-hematological diseases. A retrospective study including 33 individuals (age 9-79 yr) was conducted. It was observed that the dimensions related to physical pain, psychological discomfort, and social incapacity had statistically significant values. The most frequently performed dental treatments were periodontal treatment (45.45 %), dental restoration (36.36 %), tooth extractio n (33.33 %), and endodontic treatment (24.24 %). Thus, poor oral health directly affects the quality of life. Dental management should consider the aspects of the disease and antineoplastic treatment while aiming for safe and effective dental care.


RESUMEN: El objetivo de este estudio fue evaluar la relación entre el estado de salud oral y su impacto en la calidad de vida, y sugerir estrategias de manejo odontológico en pacientes sometidos a terapia anti-neoplásica por enfermedades onco-hematológicas. Se realizó un estudio retrospectivo que incluyó a 33 personas (de 9 a 79 años de edad). Se observó que las dimensiones relacionadas con dolor físico, malestar psicológico e incapacidad social tuvieron valores estadísticamente significativos. Los tratamientos dentales realizados con mayor frecuencia fueron el tratamiento periodontal (45,45 %), la restauración dental (36,36 %), la extracción dentaria (33,33 %) y el tratamiento endodóntico (24,24 %). Así, la mala salud oral afecta directamente la calidad de vida. El tratamiento dental debe tener en cuenta los aspectos de la enfermedad y el tratamiento antineoplásico mientras se busca una atención dental segura y eficaz.

2.
RFO UPF ; 25(3): 384-390, 20201231. tab
Article in English | LILACS, BBO | ID: biblio-1357818

ABSTRACT

Objetivo: o presente estudo teve como objetivo avaliar a eficácia de alternativas didáticas, como a mídia audiovisual, na transmissão de informações sobre os efeitos adversos orais do tratamento oncológico em pacientes com câncer. Métodos: pacientes oncológicos foram divididos aleatoriamente em dois grupos: grupo controle (n = 40) e grupo audiovisual (n = 36). O grupo controle recebeu informações verbais sobre os efeitos colaterais orais do tratamento do câncer. Por outro lado, o grupo audiovisual recebeu a mesma informação verbal, juntamente com uma apresentação ilustrativa de mídia audiovisual. Além disso, foram aplicados questionários sobre o assunto antes e após a intervenção da equipe odontológica. Resultados: o presente estudo empregou o teste exato de Fisher para análise estatística, e os resultados mostraram similaridade estatística entre os dois grupos (P > 0,05). Ambas as abordagens educacionais alcançaram o objetivo pretendido. Conclusão: um diálogo bem conduzido pode criar uma compreensão adequada entre pacientes com câncer, melhorando a sua adaptação. Opcionalmente, o uso de técnicas inovadoras, como recursos audiovisuais, pode ser uma alternativa acessível e eficiente, que também pode ser usada na educação desses pacientes. Dessa forma, vídeos educacionais podem ser usados para melhorar a compreensão dos pacientes, a adesão a esquemas terapêuticos e a qualidade de vida, além de contribuir para um melhor prognóstico.(AU)


Objective: the present study aimed to evaluate the efficacy of didactic alternatives, namely the audiovisual media, in conveying information regarding the oral adverse effects of oncology treatment in cancer patients. Methods: cancer patients were randomly divided into two groups: control group (n = 40) and audiovisual group (n = 36). The control group received verbal information regarding the oral side effects of cancer treatment. Conversely, the audiovisual group received the same verbal information, along with an illustrative audiovisual media presentation. Additionally, questionnaires on the subject were administered before and after the intervention by the dental team. Results: the current study employed Fisher's exact test for statistical analysis, and the results showed statistical similarity between the two groups (P > 0.05). Both educational approaches achieved the intended objective. Conclusion: a well-conducted dialogue can create adequate awareness among cancer patients and improve adaptation. Optionally, the use of innovative techniques, such as audiovisual resources, was observed to be an accessible and efficient alternative that can also be used in patient education. Therefore, educational videos can be used to improve patients' understanding, adherence to therapeutic regimens, and quality of life and contribute to a better prognosis.(AU)


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Audiovisual Aids/statistics & numerical data , Patient Education as Topic/methods , Antineoplastic Protocols , Antineoplastic Agents/adverse effects , Oral Health , Surveys and Questionnaires , Patient Compliance , Mouth Diseases/etiology
3.
Int. j. odontostomatol. (Print) ; 13(2): 198-202, jun. 2019. graf
Article in English | LILACS | ID: biblio-1002306

ABSTRACT

ABSTRACT: Florid osseous dysplasia (FOD) is an extensive form of osseous dysplasia where normal trabecular bone is substituted by fibrous connective tissue and amorphous mineralized tissue. Usually, the lesions are mainly asymptomatic and the patients should be followed with clinical and imaging examination, requiring no intervention. Nevertheless, due to the poor vascularization of the lesion and to local trauma, secondary infections and osteomyelitis may occur. Patients may present with pain, mucosal ulceration, lesion exposure in the oral cavity, fistula and swelling. In such cases, the correct diagnosis and management of the lesion is decisive to reestablish patient's health and quality of life. The aim of this article is to present a case of complicating secondary chronic osteomyelitis treated successfully with conservative intervention. A 68-year-old black female patient reported a "swelling of the gums" that was present for eleven years, with episodes of periodic pain and swelling. On physical examination, a papule with suppuration in the alveolar mucosa in the right side of the mandible was observed. Panoramic radiography and CBCT showed a mixed lesion surrounded by sclerotic bone. The patient was diagnosed with chronic osteomyelitis in association with FOD and treated with antibiotic therapy together with surgical curettage. The incidence, etiophatology, differential diagnosis, treatment and prevention of secondary osteomyelitis associated with FOD are discussed in the light of literature. This information might assist the dentists while choosing the best treatment options for similar cases.


RESUMEN: La displasia ósea florida (DOF) es una forma de displasia ósea donde el hueso trabecular normal es sustituido por tejido conectivo fibroso y tejido mineralizado amorfo. En general, las lesiones son de origen asintomático y los pacientes deben ser seguidos con el examen clínico. Sin embargo, debido a la pobre vascularización de la lesión y al trauma local, pueden producirse lesiones secundarias y osteomielitis. Los pacientes pueden presentarse con dolor, ulceración mucosa, lesión de exposición en la cavidad oral, fístula y edema. En estos casos, el correcto diagnóstico y tratamiento de la lesión es decisivo para reestabilizar la salud y la calidad de la vida. El objetivo de este artículo consistió en presentar un caso de complicación secundaria crónica de osteomielitis tratados con tratamiento conservador. El paciente, negro, de 68 años de edad, consulta por "hinchazón de las encías" que se presentó durante once años, con episodios de dolor. En el examen intraoral, se observó una pápula con supuración en la mucosa alveolar en el lado derecho de la mandíbula. La radiografía panorámica y CBCT mostraron una lesión mixta rodeada de hueso esclerótico. El paciente fue diagnosticado con osteomielitis crónica en asociación con DOF y fue tratado con tratamiento antibiótico junto con curetaje quirúrgico. La incidencia, la etiopatología, el diagnóstico diferencial, el tratamiento y la prevención de la osteomielitis secundaria asociada con DOF se discuten a la luz de la literatura. Esta información puede ayudar a los dentistas a elegir las mejores opciones de tratamiento para casos similares.


Subject(s)
Humans , Aged , Osteomyelitis/therapy , Osteomyelitis/diagnostic imaging , Mandibular Diseases/therapy , Conservative Treatment/methods , Radiography, Panoramic , Mandibular Diseases/diagnostic imaging , Fibrous Dysplasia of Bone/therapy , Fibrous Dysplasia of Bone/diagnostic imaging
4.
Einstein (Säo Paulo) ; 16(3): eAO4245, 2018. tab
Article in English | LILACS | ID: biblio-953169

ABSTRACT

ABSTRACT Objective To evaluate the oral health of patients with head and neck cancer after antineoplastic treatment, and to compare them with patients with no history of cancer. Methods A total of 75 patients, divided into Study Group, composed of individuals after antineoplastic treatment (n=30), and Control Group, with individuals with no history of cancer (n=45), aged 37 to 79 years. The oral health status was evaluated through the index of decayed, missing or filled permanent teeth (DMFT), community periodontal index and evaluation of the use and need of prosthesis. All of these items were evaluated according to the criteria recommended by the World Health Organization. The statistical analysis was descriptive and used the Pearson's χ2 test. Results The community periodontal index was higher in the Study Group when compared to the Control Group (p<0.0001). The need for an upper (p<0.001) and lower (p<0.0001) prostheses was higher in the Study Group. Also, the use of upper prosthesis was higher in the Study Group (p<0.002). The missing or filled permanent teeth index between the two groups (p>0.0506) and the use of lower prosthesis (p>0.214) did not present a relevant statistical difference. Conclusion Periodontal disease and edentulism are the most significant changes in individuals who received antineoplastic therapy for head and neck cancer as well as greater need for oral rehabilitation.


RESUMO Objetivo Avaliar a saúde bucal de pacientes com câncer de cabeça e pescoço após tratamento antineoplásico, e compará-los com pacientes sem histórico de câncer. Métodos Foram avaliados 75 pacientes, divididos em Grupo de Estudo de indivíduos após tratamento antineoplásico (n=30) e Grupo de Controle de indivíduos sem histórico de câncer (n=45), com faixa etária de 35 a 79 anos. A condição de saúde oral foi avaliada pelo índice de dentes permanentes cariados, perdidos e obturados (CPOD), pelo índice periodontal comunitário e por uma avaliação de uso e necessidade de prótese, conforme critérios preconizados pela Organização Mundial da Saúde. A análise estatística foi descritiva e realizada por meio do teste do χ2 de Pearson. Resultados O índice periodontal comunitário foi maior no Grupo de Estudo quando comparado ao controle (p<0,0001). A necessidade de prótese superior (p<0,001) e inferior (p<0,0001) foi maior no Grupo de Estudo. O uso de prótese superior foi maior no Grupo de Estudo (p<0,002). O índice de dentes permanentes cariados, perdidos e obturados entre os dois grupos (p>0,0506) e o uso de prótese inferior (p>0,214) não apresentaram diferença estatística relevante. Conclusão A doença periodontal e o edentulismo são as alterações mais significativas em indivíduos que receberam terapia antineoplásica de câncer de cabeça e pescoço, assim como maior necessidade de reabilitação oral.


Subject(s)
Humans , Male , Female , Adult , Aged , Periodontal Diseases/etiology , Radiotherapy/adverse effects , Oral Health , Dental Caries/etiology , Head and Neck Neoplasms/drug therapy , Head and Neck Neoplasms/radiotherapy , Antineoplastic Agents/adverse effects , Brazil , Case-Control Studies , Periodontal Index , DMF Index , Dental Prosthesis/statistics & numerical data , Head and Neck Neoplasms/physiopathology , Middle Aged
5.
J. appl. oral sci ; 26: e20170288, 2018. tab, graf
Article in English | LILACS, BBO | ID: biblio-893711

ABSTRACT

Abstract Idiopathic Bone Cavity (IBC) or Simple Bone Cyst (SBC) is a non- epithelialized bone cavity with serosanguinous fluid content or empty. There is a literature debate regarding its pathogenesis that remains unclear. The main treatment option is the surgical exploration, although there are successful cases described in the literature in which just a follow-up with clinical and radiographic evaluation was performed. Objective This study aimed to assess the spontaneous resolution of idiopathic bone cavity untreated by surgery. Material and Methods Twenty-one patients diagnosed with surgically untreated IBC were submitted to a follow-up protocol modified from Damante, Guerra, and Ferreira5 (2002). A clinical and radiographic evaluation was performed in 13 patients (13/21), while eight patients (8/21) were only radiographically evaluated. Three observers evaluated the panoramic radiographs of 21 patients and the Kappa test was performed by intra and inter-examiners. Inductive and descriptive statistics were applied to the results. Results Only one patient had a positive response to palpation and percussion of the teeth in the cyst area. Most of the cysts evaluated were rated as 3 (lesion "in involution"), 4 (lesion "almost completely resolved"), or 5 ("completely resolved"). Conclusions We observed progressive spontaneous resolution of IBC. Most cysts were found in the recovery process in different follow-up periods. Patient's follow-up, without surgery, may be considered after the diagnosis based on epidemiological, clinical, and radiographic features of the lesion.


Subject(s)
Humans , Male , Female , Child , Adolescent , Adult , Young Adult , Remission, Spontaneous , Bone Cysts/pathology , Mandibular Diseases/pathology , Time Factors , Bone Cysts/physiopathology , Bone Cysts/diagnostic imaging , Radiography, Panoramic , Mandibular Diseases/physiopathology , Mandibular Diseases/diagnostic imaging , Sex Factors , Age Factors , Cone-Beam Computed Tomography
6.
ImplantNews ; 11(6a): 175-180, 2014. ilus
Article in Portuguese | LILACS, BBO | ID: lil-733628

ABSTRACT

Objetivo: o objetivo deste estudo foi avaliar a prevalência das calcificações na artéria carótida – CACs – em imagens digitais panorâmicas (PD) e de tomografia computadorizada de feixe cônico (TCFC) dos mesmos pacientes. A CAC é uma doença vascular que acomete os pacientes acima dos 50 anos, coincidindo com uma grande maioria de pacientes que procura reabilitação por implantes. Assim sendo, é importante que o implantodontista esteja atento à interpretação da CAC, uma vez que detectada requer encaminhamento do paciente a um cardiologista para confirmação do diagnóstico. Material e métodos: foram avaliadas 100 imagens (200 lados) de panorâmicas digitais (idade média de 48 anos) e a imagem TCFC dos mesmos pacientes. O re-exame das imagens panorâmicas foi realizado com o objetivo de identificar os CACs falso-positivos e falso-negativos em relação à TCFC. Resultados: considerando 200 lados analisadas, 3,5% (n=7/200) foram interpretadas como CACs em radiografias panorâmicas, e 2,5% (n=5/200) em imagens de TCFC. Dos sete casos CACs positivos em radiografias panorâmicas, três foram falso-positivos quando comparados à correspondente TCFC. Quanto aos cinco casos CACs positivos em TCFC, um era falso-negativo, comparado à imagem panorâmica respectiva. Conclusão: calcificações artéria carótida – CACs – podem ser vistas nas imagens panorâmicas e/ou TCFC, no entanto, a panorâmica tendeu a mostrar casos falso-positivos da CAC. A CAC surge como um achado incidental nos exames de panorâmica e de TCFC, mas ainda assim o dentista tem como obrigação encaminhar o paciente para um cardiologista para a confirmação do diagnóstico, uma vez detectada a sua suposta presença.


Subject(s)
Humans , Carotid Artery Diseases , Carotid Stenosis , Cone-Beam Computed Tomography , Radiography, Panoramic
7.
ImplantNews ; 9(6a): 154-157, 2012.
Article in Portuguese | LILACS, BBO | ID: biblio-851005

ABSTRACT

O forâmen mentual é um importante ponto de referência cirúrgico, sua localização e a possibilidade da existência de uma alça anterior do nervo mentual deve ser levada em consideração no planejamento cirúrgico para evitar traumas ao nervo. Nesse trabalho, avaliamos a presença da alça anterior do nervo mentual em 70 pacientes por meio de tomografia computadorizada de feixe cônico (TCFC). Os resultados revelaram uma prevalência de 32,8% da alça anterior. Nossos resultados e os encontrados na literatura atentam para uma imprevisibilidade das variações anatômicas na região do forâmen mentual. Assim, um planejamento individualizado para cada paciente deveria ser feito para minimizar os riscos de complicações pós-operatórias. A TCFC poderia ser indicada para os pacientes nos quais a anatomia da região do forâmen mentual não possa ser claramente visualizada em outros exames


The mental foramen is a surgical strategically landmark its location and the possibility of an anterior loop of the mental nerve exists mesial to the mental foramen needs to be take in consideration before implant placement to avoid nerve injury. We studied the presence of the anterior loop of mental nerve by means of CBCT in 70 patients. The results revealed a prevalence of 32,8%. Our findings together with the literature reviewed draw attention to the unpredictability of anatomical variations. Therefore, individualized anatomic assessment for each patient should be performed to minimized surgical complications. CBCT can be indicated in the cases where the anatomy of the mental foramen region is not clearly depicted in other exams


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Cranial Nerves , Tomography
8.
J. appl. oral sci ; 19(5): 500-504, Sept.-Oct. 2011. ilus, tab
Article in English | LILACS | ID: lil-600840

ABSTRACT

OBJECTIVE: This study evaluated experimentally-induced periapical bone loss sites using digital radiographic and histopathologic parameters. MATERIAL AND METHODS: Twenty-seven Wistar rats were submitted to coronal opening of their mandibular right first molars. They were radiographed at 2, 15 and 30 days after the operative procedure by two digital radiographic storage phosphor plates (Digora®). The images were analyzed by creating a region of interest at the periapical region of each tooth (ImageJ) and registering the corresponding pixel values. After the sacrifice, the specimens were submitted to microscopic analysis in order to confirm the pulpal and periapical status of the tooth. RESULTS: There was significant statistically difference between the control and test sides in all the experimental periods regarding the pixel values (two-way ANOVA; p<0.05). CONCLUSIONS: The microscopic analysis proved that a periapical disease development occurred during the experimental periods with an evolution from pulpal necrosis to periapical bone resorption.


Subject(s)
Animals , Rats , Bone Resorption , Dental Pulp Necrosis , Periapical Diseases , Bone Resorption/pathology , Bone Resorption , Dental Pulp Necrosis/pathology , Dental Pulp Necrosis , Periapical Diseases/pathology , Periapical Diseases , Radiographic Image Enhancement , Rats, Wistar , Radiography, Dental, Digital/methods , Time Factors
9.
J. appl. oral sci ; 18(5): 538-541, Sept.-Oct. 2010. ilus
Article in English | LILACS | ID: lil-564192

ABSTRACT

Pyogenic granuloma (PG) is a benign non-neoplastic mucocutaneous lesion. It is a reactional response to constant minor trauma and might be related to hormonal changes. In the mouth, PG is manifested as a sessile or pedunculated, resilient, erythematous, exophytic and painful papule or nodule with a smooth or lobulated surface that bleeds easily. PG preferentially affects the gingiva, but may also occur on the lips, tongue, oral mucosa and palate. The most common treatment is surgical excision. This paper describes a mucocutaneous PG on the upper lip, analyzing the clinical characteristics and discussing the features that distinguish this lesion from other similar oral mucosa lesions. The diagnosis of oral lesions is complex and leads the dentist to consider distinct lesions with different diagnostic methods. This case report with a 4 year-follow-up calls the attention to the uncommon mucocutaneous labial location of PG and to the fact that surgical excision is the safest method for diagnosis and treatment of PG of the lip, even when involving the mucosa and skin.


Subject(s)
Child , Female , Humans , Granuloma, Pyogenic/surgery , Lip/injuries , Biopsy , Follow-Up Studies , Granuloma, Pyogenic/etiology , Lip Diseases/surgery , Mouth Mucosa/injuries
10.
ImplantNews ; 7(6): 859-861, 2010. ilus
Article in Portuguese | LILACS, BBO | ID: lil-599220

ABSTRACT

Muitas situações exigem o uso de técnicas de processamento de imagens, por exemplo, no realce de bordas, onde a aplicação de ferramentas matemáticas é fundamental para o sucesso da sua visualização. Este artigo apresenta a utilização de ferramentas matemáticas na análise e processamento de imagens digitais obtidas por meio de microscopia eletrônica de varredura. Nesse estudo em particular, o realce da interface entre implante/pilar foi necessário como uma etapa anterior a medição do desajuste vertical entre ambos.


The image processing tools have many applications in Dentistry, including Implantology. Particularly for edge detection, the algorithm operations are fundamental to the edge visualization success. This paper shows the use of such mathematic tool in the analysis and processing of digital images obtaining by means of scanning electron microscope (SEM). In this paper, the edge detection enhancement of the implant/abutment interface allowed for the measurement of the vertical margin fit.


Subject(s)
Dental Implants , Image Processing, Computer-Assisted , Microscopy, Electron, Scanning
11.
Pesqui. bras. odontopediatria clín. integr ; 8(2): 233-244, maio-ago. 2008. tab
Article in Portuguese | LILACS, BBO | ID: biblio-873634

ABSTRACT

Objetivo: Avaliar o momento de aquisição de estreptococos mutans(EM), desenvolvimento de cárie dental e as variáveis a elesassociadas no decorrer de 23 meses, em primogênitos de famíliasde baixo nível socioeconômico, desde os sete meses de idade.Método: A amostra foi selecionada com base em mães densamentecolonizadas por EM, incluindo todos os membros de 14 famílias queconviviam na mesma casa. Foram envolvidos no estudo 14 mães,pais e primogênitos e 8 parentes, na maioria avós. Exames clínicose radiográficos iniciais determinaram os índices de cárie e condiçãoperiodontal dos adultos. Contagens de EM foram feitas em todosos adultos nas duas primeiras visitas. Nas crianças foram avaliadosos níveis de EM, o número de dentes e de cáries, em quatro visitas.Resultados: A prevalência de EM nos adultos foi alta, estandoausente em apenas um dos pais. EM foram detectados em 1, 2, 3 e10 crianças, respectivamente nas visitas #1, 2, 3 e 4. A cárie dentalfoi detectada em apenas três crianças na última visita (aos 30meses de idade), as quais apresentaram escores de EMsignificantemente maiores que as crianças sem cárie, na mesmavisita.Conclusão: Exclusivamente a condição social de baixa renda emães densamente colonizadas por EM não são sinônimo decolonização precoce e alta atividade de cárie em crianças cuidadasem casa. O desenvolvimento de cárie está significantementeassociado a escores elevados de EM nas crianças.


Subject(s)
Infant, Newborn , Infant , Child , Adult , Middle Aged , Humans , Male , Female , Dental Caries/diagnosis , Tooth, Deciduous , Oral Hygiene/education , Streptococcus mutans/pathogenicity , Chi-Square Distribution , Statistics, Nonparametric
12.
J. appl. oral sci ; 15(1): 14-17, Jan.-Feb. 2007. tab, graf
Article in English | LILACS | ID: lil-450004

ABSTRACT

OBJECTIVES: This study applied a simple method to evaluate the performance of three digital devices (two scanners and one digital camera) using the reproducibility of pixel values attributed to the same radiographic image. METHODS: Using the same capture parameters, a radiographic image was repeatedly digitized in order to determine the variability of pixel values given to the image throughout the digitization process. One coefficient value was obtained and was called pixel value reproducibility. RESULTS: A significant difference in pixel values was observed among the three devices for the digitized images (ANOVA, p<0.00001). There was significant pixel value variability at the same digitization conditions for one scanner and the digital camera. CONCLUSIONS: Digital devices may assign pixel values differently in consecutive digitization depending on the optical density of the radiographic image and the equipment. The pixel value reproducibility was not satisfactory as tested for two devices. It is maybe advisable knowing the digitization variations regarding pixel values whenever using digital radiography images in longitudinal clinical examinations.

13.
Braz. oral res ; 21(3): 272-277, 2007. graf, tab
Article in English | LILACS | ID: lil-458602

ABSTRACT

The aim of this study was to evaluate the oral sequelae of radiotherapy in patients treated between 1999 and 2003 for head and neck tumors. One-hundred patients (24 women, 76 men) ranging in age from 30 to 83 years (mean 59.2 years) were examined. Time since radiotherapy ranged from 1 to 72 months (mean 28 months). The total mean radiation dose received by the patients was 5,955 cGy. The evaluation protocol included anamnesis, intraoral and extraoral examination, measurement of stimulated salivary flow and salivary pH. Symptoms reported by the patients included dry mouth (68 percent), dysphagia (38 percent), and dysgeusia (30 percent). In 64 percent of the patients, the mean stimulated salivary flow rate was less than 0.7 ml/min. The mean salivary pH was 6.97 (± 0.714). Stimulated salivary flow increased with increasing postradiotherapy time (p < 0.05). The prevalence of mucositis was associated with higher radiation doses (p < 0.05), and the prevalence of atrophic candidiasis was related to a longer post-treatment period (p < 0.05). Two cases of recurrence of the primary tumor were detected during the study. The main effect of radiotheraphy in the head and neck region was a reduction of the salivary flow rate, even though our study demonstrated that there was a modest late improvement of the salivary flow.


O objetivo deste estudo foi avaliar as seqüelas bucais provocadas pela radioterapia em pacientes com neoplasias de cabeça e pescoço, tratados entre 1999 e 2003. Foram examinados 100 pacientes (24 mulheres e 76 homens), com idades entre 30 e 83 anos (média de 59,2 anos). O tempo desde a radioterapia variou de 1 a 72 meses (média de 28 meses). A média da dose total de radiação recebida pelos pacientes foi de 5.955 cGy. O protocolo de avaliação consistiu de anamnese, exame físico, aferição do fluxo salivar estimulado e pHmetria da saliva. Os sintomas referidos foram boca seca (68 por cento), disfagia (38 por cento) e disgeusia (30 por cento). Em 64 por cento dos indivíduos o valor médio do fluxo salivar estimulado esteve abaixo de 0.7 ml/min. O pH médio da amostra foi de 6.97 (± 0.714). O fluxo estimulado e a ocorrência de candidíase atrófica aumentaram conforme o aumento do tempo pós-radioterapia (p < 0.05). A ocorrência de mucosite esteve associada a maiores doses de radiação (p < 0.05). Dois casos de segundo tumor primário foram diagnosticados. O principal efeito da radioterapia na região de cabeça e pescoço foi a redução do fluxo salivar, apesar de nosso estudo ter demonstrado que há uma melhora tardia do fluxo salivar.


Subject(s)
Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Cranial Irradiation/adverse effects , Mouth Mucosa/radiation effects , Salivation/radiation effects , Xerostomia/etiology , Carcinoma, Squamous Cell/radiotherapy , Dose-Response Relationship, Radiation , Head and Neck Neoplasms/radiotherapy , Linear Models , Osteoradionecrosis/etiology , Secretory Rate , Saliva , Salivary Glands/radiation effects
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